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Protein Coding Gene : Hsph1 heat shock 105kDa/110kDa protein 1
Primary Identifier  MGI:105053 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  15505
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables alpha-tubulin binding activity. Acts upstream of or within chaperone cofactor-dependent protein refolding. Colocalizes with microtubule. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and limb. Orthologous to human HSPH1 (heat shock protein family H (Hsp110) member 1).
PHENOTYPE: Homozygous inactivation of this gene leads to decreased susceptibility to ischemic brain injury. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-32092,
  • AI790491,
  • HSP110,
  • Hsph1,
  • heat shock protein 105,
  • MGI:2140965,
  • Hsp110,
  • heat shock protein 110,
  • hsp-E7I,
  • heat shock 105kDa/110kDa protein 1,
  • Hsp105,
  • hsp110/105,
  • expressed sequence AI790491
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Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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