Primary Identifier | MGI:1350929 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 27053 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity and identical protein binding activity. Predicted to be involved in several processes, including asparagine biosynthetic process; cellular response to glucose starvation; and positive regulation of mitotic cell cycle. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and respiratory system. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). PHENOTYPE: Mice homozygous for a hypomophic allele exhibit structural brain abnormalities, including enlarged ventricles and reduced cortical thickness, and deficits in short- and long-term memory. [provided by MGI curators] |