Primary Identifier | MGI:1919027 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 71777 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methylated histone binding activity. Predicted to contribute to histone H2A acetyltransferase activity and histone H4 acetyltransferase activity. Predicted to be involved in positive regulation of double-strand break repair via homologous recombination and regulation of cell cycle. Predicted to be located in nucleoplasm. Predicted to be part of chromatin and piccolo histone acetyltransferase complex. Is expressed in several structures, including central nervous system; early conceptus; foregut; genitourinary system; and sensory organ. Orthologous to human ING3 (inhibitor of growth family member 3). PHENOTYPE: Mice homozygous for a transgene disruption of the gene exhibit abnormal embryonic development and brain formation with lethality between E10.5 and birth. [provided by MGI curators] |