Primary Identifier | MGI:2136018 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 93735 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within bone remodeling and cardiac epithelial to mesenchymal transition. Predicted to be located in cytoplasm. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and heart. Orthologous to human WNT16 (Wnt family member 16). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased bone mineral density, cortical bone thickness and bone strength. [provided by MGI curators] |