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Protein Coding Gene : Tspan33 tetraspanin 33
Primary Identifier  MGI:1919012 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  232670
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables enzyme binding activity. Involved in pore complex assembly; protein localization to plasma membrane; and protein maturation. Located in cell surface and tetraspanin-enriched microdomain. Part of pore complex. Is expressed in embryo; liver; and liver lobe. Orthologous to human TSPAN33 (tetraspanin 33).
PHENOTYPE: Mice homozygous for a null mutation display anemia and partial penetrance of red blood cell abnormalities, splenomegaly, monocytosis, thrombocytopenia, reticulocytosis, and extramedullary hematopoiesis. [provided by MGI curators]
  • synonyms:
  • MGI:2144063,
  • Pen,
  • tetraspanin 33,
  • RIKEN cDNA 1300010A20 gene,
  • expressed sequence AI035228,
  • Penumbra,
  • AI035228,
  • 1300010A20Rik,
  • Tspan33
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