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Protein Coding Gene : Strip2 striatin interacting protein 2
Primary Identifier  MGI:2444363 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  320609
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to be involved in cell migration; cytoskeleton organization; and regulation of cell shape. Predicted to be located in cytoplasm. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in cytosol. Is expressed in brain and cochlea epithelium. Orthologous to human STRIP2 (striatin interacting protein 2).
PHENOTYPE: Homozygous knockout affects cardiac muscle contractility under basal conditions and worsening pulmonary congestion and cardiac phenotypes (muscle contractility reduction, hypertrophy, fibrosis) under pressure overload. [provided by MGI curators]
  • synonyms:
  • D330017J20Rik,
  • striatin interacting protein 2,
  • RIKEN cDNA D330017J20 gene,
  • family with sequence similarity 40, member B,
  • Fam40b,
  • Strip2,
  • Myoscape,
  • mKIAA1170
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