| Primary Identifier | MGI:101918 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 11997 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable geranylgeranyl reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; and retinal dehydrogenase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to act upstream of or within lipid metabolic process. Located in mitochondrion. Is expressed in several structures, including adrenal gland and genitourinary system. Orthologous to several human genes including AKR1B10 (aldo-keto reductase family 1 member B10). PHENOTYPE: Mice homozygous for a null allele exhibit disrupted progesterone levels during estrous. Mice homozygous for a different knock-out allele exhibit increased basal adiposity and susceptibility to diet-induced obesity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
