| Primary Identifier | MGI:1914955 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 67705 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Involved in mitochondrion organization; positive regulation of NLRP3 inflammasome complex assembly; and positive regulation of interleukin-1 beta production. Located in mitochondrial intermembrane space and mitochondrial outer membrane. Is active in mitochondrial inner membrane. Is expressed in retina. Orthologous to human STMP1 (short transmembrane mitochondrial protein 1). PHENOTYPE: Homozygous null mice show normal cardiac function but cardiac mitochondria show altered complex III assembly dynamics and reduced complex III activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
