Primary Identifier | MGI:1917173 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 69923 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATP-dependent diacylglycerol kinase activity; acylglycerol kinase activity; and ceramide kinase activity. Acts upstream of or within ceramide biosynthetic process and lipid phosphorylation. Located in membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase). PHENOTYPE: T cell specific knockout reduces CD8+ T cell proliferation and antitumor immune responses. [provided by MGI curators] |