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Protein Coding Gene : Prss3b serine protease 3B

Primary Identifier  MGI:1914623 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67373
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables serine-type endopeptidase activity. Acts upstream of or within zymogen activation. Predicted to be active in extracellular space. Is expressed in ductus deferens; gallbladder; pancreas; pancreas tip epithelium; and testis. Used to study pancreatitis.
PHENOTYPE: Mice homozygous for an autoactivated allele are runted and die by 2 months of age. Mice heterozygous for the allele develop acute and chronic pancreatitis. [provided by MGI curators]
  • synonyms:
  • serine protease 3B,
  • T7,
  • cationic trypsinogen (isoform T7),
  • expressed sequence AV072249,
  • MGI:2141617,
  • RIKEN cDNA 2210010C04 gene,
  • Prss3b,
  • 2210010C04Rik,
  • AV072249,
  • MGI:7388428

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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