| Primary Identifier | MGI:108011 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 18291 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within ovarian follicle development. Located in cytoplasm. Is expressed in several structures, including eye; genitourinary system; heart; liver; and musculoskeletal system. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 5. Orthologous to human NOBOX (NOBOX oogenesis homeobox). PHENOTYPE: Mice homozygous for disruptions in this gene display oocyte degeneration after birth, atrophic ovaries, and female infertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
