Primary Identifier | MGI:1889817 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 58887 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin insulator sequence binding activity and sequence-specific DNA binding activity. Involved in regulation of fatty acid transport and regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of D-glucose import. Located in cytosolic ribosome; lipid droplet; and nuclear membrane. Is expressed in central nervous system and genitourinary system. Orthologous to human REPIN1 (replication initiator 1). PHENOTYPE: Mice homozygous for a knock-out allele improves in insulin sensitivity and glucose metabolism in Leprdb homozygotes. [provided by MGI curators] |