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Protein Coding Gene : Gimap6 GTPase, IMAP family member 6

Primary Identifier  MGI:1918876 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  231931
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTP binding activity. Acts upstream of or within several processes, including autophagy; cell redox homeostasis; and defense response to other organism. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system. Orthologous to human GIMAP6 (GTPase, IMAP family member 6).
PHENOTYPE: Conditional homozygous knockout in lymphocytes affects autophagy and mitophagy in peripheral T cells and increases apoptosis and decreases the numbers of these T cells. [provided by MGI curators]
  • synonyms:
  • GTPase, IMAP family member 6,
  • immune associated nucleotide 6,
  • RIKEN cDNA 4833419H03 gene,
  • Gimap6,
  • 4833419H03Rik,
  • Ian6

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Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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