Primary Identifier | MGI:1926488 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 60531 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Predicted to be involved in negative regulation of gonadotropin secretion and neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in brain; cerebral cortex; dorsomedial hypothalamic nucleus; hypothalamus; and hypothalamus mantle layer. Orthologous to human NPVF (neuropeptide VF precursor). PHENOTYPE: Mice in which conditional deletion occurs in the nervous system exhibit intensive wheel running after light-off and decreased wheel running during other times, reduced pain sensitivity, and decreased anxiety-related behavior. [provided by MGI curators] |