Primary Identifier | MGI:107208 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 15397 |
Mgi Type | lncRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within regulation of transcription by RNA polymerase II. Is expressed in several structures, including epidermis; genitourinary system; limb; limb bud; and stomach proventricular region epithelium. Orthologous to human HOXA11-AS (HOXA11 antisense RNA). PHENOTYPE: Mice homozygous for a knock-out allele develop mild spontaneous intestinal inflammation as they age and show impaired mitochondrial OXPHOS in cells of the distal colon and increased susceptibility to experimental models of induced colitis. [provided by MGI curators] |