Primary Identifier | MGI:95461 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 14028 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryo development; generation of neurons; and positive regulation of transcription by RNA polymerase II. Located in axon and neuronal cell body. Is expressed in several structures, including alimentary system; central nervous system; egg cylinder; genitourinary system; and limb bud. Orthologous to human EVX1 (even-skipped homeobox 1). PHENOTYPE: Homozygotes for a particular targeted mutation are embryonic lethal. Another heritable cre-generated allele exhibits defects of the interneurons of the ventral spinal cord, and rarely, a kinked tail. [provided by MGI curators] |