| Primary Identifier | MGI:1915419 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 68169 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heparin binding activity. Involved in gonadotrophin-releasing hormone neuronal migration to the hypothalamus; response to ischemia; and vascular wound healing. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including brain; embryo mesenchyme; intervertebral disc; lung; and molar. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism. Orthologous to human NDNF (neuron derived neurotrophic factor). PHENOTYPE: Mice homozygous for a null allele exhibit enhanced skeletal muscle atrophy in dexamethasone infusion and sciatic denervation models of muscle atrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
