| Primary Identifier | MGI:3511278 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 232077 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including otic placode development; parathyroid gland development; and pharyngeal system development. Is active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; exocrine system; integumental system; and sensory organ. Used to study Goldenhar syndrome. Orthologous to human FOXI3 (forkhead box I3). PHENOTYPE: Homozygous null mice start dying after E9.5. Those born die neonatally, lack a mouth and whiskers, and show branchial arch-derived skeletal defects, including a reduced mandible, total absence of inner, middle and external ear structures, and increased cranial neural crest cell apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
