Primary Identifier | MGI:97896 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 19693 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including molecular function inhibitor activity; oligosaccharide binding activity; and peptidoglycan binding activity. Acts upstream of or within myelination and suckling behavior. Located in collagen-containing extracellular matrix. Is expressed in several structures, including gut; male reproductive gland or organ; and mesenteric adipose tissue. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to several human genes including REG1A (regenerating family member 1 alpha). PHENOTYPE: Mice homozygous for a null allele exhibit impaired suckling, delayed hypoglossal myelination and reduced liver regeneration following partial hepatectomy. [provided by MGI curators] |