Primary Identifier | MGI:1315200 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 110958 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in female gamete generation; male meiosis chromosome separation; and spermatogenesis. Located in cytoplasm. Is expressed in lung and reproductive system. Human ortholog(s) of this gene implicated in spermatogenic failure 48. Orthologous to human M1AP (meiosis 1 associated protein). PHENOTYPE: Mice homozygous for a gene trap allele exhibit male infertility with oligospermia, globozooaspermiam decreased testies weight and size, degeneration of seminiferous tubules, male germ cell apoptosis and arrested male meiosis. [provided by MGI curators] |