| Primary Identifier | MGI:1342288 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 16815 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including positive regulation of convergent extension involved in gastrulation; positive regulation of non-canonical Wnt signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including adrenal cortex; central nervous system; genitourinary system; neural retina; and vibrissa. Orthologous to human LBX2 (ladybird homeobox 2). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and healthy with no gross developmental defects. [provided by MGI curators] |