| Primary Identifier | MGI:2446229 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 194388 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 5-methylcytosine dioxygenase activity. Involved in epigenetic programing of male pronucleus. Acts upstream of or within positive regulation of gene expression via chromosomal CpG island demethylation. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; immune system; and neural ectoderm. Orthologous to human TET3 (tet methylcytosine dioxygenase 3). PHENOTYPE: Mice inheriting a null allele from a germ cell conditional null mother display impaired reprogramming of the paternal genome resulting in reduced embryo viability. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
