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Protein Coding Gene : Pcyox1 prenylcysteine oxidase 1
Primary Identifier  MGI:1914131 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  66881
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables prenylcysteine oxidase activity. Acts upstream of or within prenylcysteine catabolic process. Located in lysosome. Is expressed in several structures, including genitourinary system; integumental system; limb; nervous system; and respiratory system. Orthologous to human PCYOX1 (prenylcysteine oxidase 1).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and free of obvious pathology despite a striking accumulation of both farnesylcysteine and geranylgeranylcysteine in brain and liver. [provided by MGI curators]
  • synonyms:
  • PCL1,
  • 1200015P13Rik,
  • AI115532,
  • prenylcysteine oxidase 1,
  • MGI:1889828,
  • MGI:1353595,
  • EST AI448340,
  • Pcly,
  • AI448340,
  • Pcyox1,
  • RIKEN cDNA 1200015P13 gene,
  • EST AI115532
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