|  Help  |  About  |  Contact Us

Protein Coding Gene : Copg1 coatomer protein complex, subunit gamma 1
Primary Identifier  MGI:1858696 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  54161
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable structural molecule activity. Predicted to be involved in several processes, including Golgi vesicle transport; establishment of Golgi localization; and organelle transport along microtubule. Located in Golgi membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study combined immunodeficiency and polyclonal hypergammaglobulinemia. Orthologous to human COPG1 (COPI coat complex subunit gamma 1).
PHENOTYPE: Homozygosity for the p.K652E mutation increases ER stress in B cells and impairs immune response to bacterial infections, leading to weight loss, hunched posture and ruffled fur. [provided by MGI curators]
  • synonyms:
  • MGI:106462,
  • coatomer protein complex, subunit gamma,
  • expressed sequence AU019265,
  • BC056168,
  • AU019265,
  • D6Wsu16e,
  • coatomer protein complex, subunit gamma 1,
  • MGI:3036293,
  • D6Ertd71e,
  • DNA segment, Chr 6, Wayne State University 16, expressed,
  • cDNA sequence BC056168,
  • Copg1,
  • Copg,
  • DNA segment, Chr 6, ERATO Doi 71, expressed,
  • MGI:1098809,
  • MGI:2141561,
  • MGD-MRK-34156
Paste the following link
Lists
This ProteinCodingGene isn't in any lists. Upload a list.

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom