| Primary Identifier | MGI:1914053 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 232210 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables single-stranded DNA binding activity. Involved in double-strand break repair via alternative nonhomologous end joining; positive regulation of isotype switching; and somatic hypermutation of immunoglobulin genes. Predicted to be active in replication fork. Is expressed in several structures, including adipose tissue; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human HMCES (5-hydroxymethylcytosine binding, ES cell specific). PHENOTYPE: Homozygous knockout leads to changes in DNA methylation, resulting in an altered embryonic gene expression profile and embryonic sub-lethality (lower embryonic survival). [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
