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Protein Coding Gene : Txnrd3 thioredoxin reductase 3
Primary Identifier  MGI:2386711 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  232223
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables thioredoxin-disulfide reductase (NADPH) activity. Acts upstream of or within blastocyst formation and glutathione metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and mitochondrion. Is expressed in early conceptus; embryo; secondary oocyte; and telencephalon. Orthologous to human TXNRD3 (thioredoxin reductase 3).
PHENOTYPE: Mice exhibit reduced male fertility associated with oligozoospermia and asthenozoospermia. [provided by MGI curators]
  • synonyms:
  • MGI:1889389,
  • Tgr,
  • thioredoxin reductase 3,
  • Txnrd3,
  • EST AI196535,
  • AI196535,
  • TR2
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Trail: ProteinCodingGene

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