Primary Identifier | MGI:2443369 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232237 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human FGD5 (FYVE, RhoGEF and PH domain containing 5). PHENOTYPE: Homozygous disruption of this gene leads to complete embryonic lethality during organogenesis. [provided by MGI curators] |