Primary Identifier | MGI:1928140 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 64658 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 50. Orthologous to human MRPS25 (mitochondrial ribosomal protein S25). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic growth retardation, failure of primitive streak formation, disorganized extraembryonic tissue, and complete embryonic lethality by E9.5. [provided by MGI curators] |