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Protein Coding Gene : Tafa4 TAFA chemokine like family member 4

Primary Identifier  MGI:2444563 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  320701
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables receptor ligand activity. Involved in several processes, including macrophage chemotaxis; phagocytosis; and superoxide anion generation. Acts upstream of or within regulation of membrane potential and regulation of sensory perception of pain. Located in extracellular space. Is active in glutamatergic synapse and synaptic vesicle membrane. Is expressed in central nervous system; dorsal root ganglion; inner ear; and tooth. Orthologous to human TAFA4 (TAFA chemokine like family member 4).
PHENOTYPE: Mice homozygous for a null allele exhibit increased mechanical and chemical nociception following inflammation or injury due to alterations in lamina IIi neuron excitability. [provided by MGI curators]
  • synonyms:
  • Tafa4,
  • family with sequence similarity 19, member A4,
  • TAFA chemokine like family member 4,
  • RIKEN cDNA C130034I18 gene,
  • MGI:6276246,
  • Fam19a4,
  • C130034I18Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For