Primary Identifier | MGI:1354178 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 50501 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor binding activity. Acts upstream of or within circadian rhythm. Predicted to be located in extracellular region. Is expressed in several structures, including genitourinary system; heart; liver; lung; and telencephalon. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 4 with or without anosmia. Orthologous to human PROK2 (prokineticin 2). PHENOTYPE: Mice homozygous for a knock-out allele have a significantly reduced olfactory bulb displaying abnormal architecture and accumulation of neuronal progenitors in the rostral migratory stream. [provided by MGI curators] |