| Primary Identifier | MGI:103298 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 11810 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR AU-rich region binding activity. Involved in cytidine to uridine editing and positive regulation of gene expression via chromosomal CpG island demethylation. Acts upstream of or within several processes, including lipoprotein transport; negative regulation of metabolic process; and response to gamma radiation. Predicted to be part of apolipoprotein B mRNA editing enzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in early conceptus; genitourinary system; and liver. Orthologous to human APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1). PHENOTYPE: Mice homozygous for a null allele exhibit abnormal lipid homeostasis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
