Primary Identifier | MGI:1926805 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 60611 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in male meiosis I and spermatogenesis. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human FOXJ2 (forkhead box J2). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility associated with male meiosis arrest and unrepaired double strand breaks in spermatocytes. [provided by MGI curators] |