| Primary Identifier | MGI:2135946 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 93671 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable scaffold protein binding activity and scavenger receptor activity. Predicted to be involved in acute-phase response and vesicle-mediated transport. Predicted to be located in cell surface and plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; immune system; male reproductive gland or organ; olfactory lobe; and quadriceps femoris muscle. Orthologous to human CD163 (CD163 molecule). PHENOTYPE: After hindlimb ischemia, mice homozygous for a knock-out allele exhibit increased muscle satellite cell proliferation, and enhanced skeletal muscle regeneration not limited to the site of injury. Knock-out mice also exhibit increased eosinophilic airway inflammation in house dust mite-challenged. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
