Primary Identifier | MGI:1315192 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 16977 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in flagellated sperm motility and radial spoke assembly. Located in sperm flagellum. Is active in cytosol. Is expressed in lung; lung epithelium; nasal cavity respiratory epithelium; nasal epithelium; and palatal shelf mesenchyme. Human ortholog(s) of this gene implicated in spermatogenic failure 92. Orthologous to human LRRC23 (leucine rich repeat containing 23). PHENOTYPE: Homozygous null males are infertile due to radial spoke disorganization and impaired spermatozoa motility. [provided by MGI curators] |