| Primary Identifier | MGI:95785 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 14695 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase binding activity; signaling receptor complex adaptor activity; and spectrin binding activity. Predicted to be involved in several processes, including cell volume homeostasis; regulation of fat cell differentiation; and regulation of lipid metabolic process. Located in dendrite. Part of heterotrimeric G-protein complex. Is expressed in several structures, including brain; eye; ganglia; gut; and spleen. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; depressive disorder; familial hyperlipidemia; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal light ON response and synaptic maintenance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
