Primary Identifier | MGI:107307 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 28019 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methylated histone binding activity and transcription coactivator activity. Predicted to contribute to histone acetyltransferase activity. Involved in positive regulation of apoptotic process. Located in nucleus. Is expressed in several structures, including cerebral cortex; early conceptus; genitourinary system; sensory organ; and skeleton. Orthologous to human ING4 (inhibitor of growth family member 4). PHENOTYPE: Mice homozygous for a gene trapped allele are hypersensitive to LPS challenge and exhibit elevated cytokine responses. [provided by MGI curators] |