| Primary Identifier | MGI:1341149 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 11642 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein kinase A binding activity. Involved in establishment of protein localization and flagellated sperm motility. Acts upstream of or within blastocyst hatching; cell surface receptor protein serine/threonine kinase signaling pathway; and protein localization. Located in acrosomal vesicle and sperm principal piece. Is active in sperm fibrous sheath. Is expressed in early conceptus; secondary oocyte; and spermatocyte. Human ortholog(s) of this gene implicated in spermatogenic failure 82. Orthologous to human AKAP3 (A-kinase anchoring protein 3). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility associated with decreased hyperactivated sperm motility and abnormal sperm flagellum. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
