Primary Identifier | MGI:2136934 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 94071 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables natural killer cell lectin-like receptor binding activity. Predicted to act upstream of or within cellular defense response. Predicted to be located in cell surface and endoplasmic reticulum. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC2D (C-type lectin domain family 2 member D). PHENOTYPE: Mice homozygous for a null allele exhibit glomerular and tubular lesions, immunoglobulin renal deposits, abdominal and ectopic lipid accumulation, and kidney inflammation. [provided by MGI curators] |