Primary Identifier | MGI:2444151 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 243653 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including adrenal gland; brain; gut; heart ventricle; and lung. Human ortholog(s) of this gene implicated in aspergillosis. Orthologous to human CLEC1A (C-type lectin domain family 1 member A). PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to experimental autoimmune encephalomyelitis, with decreased recall memory T cell proliferation and decreased antigen-presenting ability of dendritic cells. [provided by MGI curators] |