Primary Identifier | MGI:2662547 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 243655 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and transmembrane signaling receptor activity. Acts upstream of or within natural killer cell activation; positive regulation of innate immune response; and positive regulation of type II interferon production. Located in external side of plasma membrane. PHENOTYPE: Homozygous null mice are viable and fertile and display impaired natural killer cell mediated allogeneic cytotoxicity. [provided by MGI curators] |