Primary Identifier | MGI:1336161 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 16641 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable HLA-E specific inhibitory MHC class Ib receptor activity and MHC class I protein complex binding activity. Predicted to be involved in positive regulation of natural killer cell mediated cytotoxicity and stimulatory C-type lectin receptor signaling pathway. Located in external side of plasma membrane. Is expressed in liver. Orthologous to several human genes including KLRC1 (killer cell lectin like receptor C1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to viral infection. [provided by MGI curators] |