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Protein Coding Gene : Pde3a phosphodiesterase 3A, cGMP inhibited
Primary Identifier  MGI:1860764 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  54611
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including oocyte maturation; positive regulation of oocyte development; and regulation of meiotic nuclear division. Located in cytosol and membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; genitourinary system; and integumental system. Human ortholog(s) of this gene implicated in hypertension and brachydactyly syndrome. Orthologous to human PDE3A (phosphodiesterase 3A).
PHENOTYPE: Homozygous null mice display female infertility with oocyte arrest. [provided by MGI curators]
  • synonyms:
  • A930022O17Rik,
  • C87899,
  • Pde3a,
  • RIKEN cDNA A930022O17 gene,
  • phosphodiesterase 3A, cGMP inhibited,
  • MGI:2141790,
  • MGI:2442709,
  • expressed sequence C87899
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