Primary Identifier | MGI:96763 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 16832 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables L-lactate dehydrogenase activity. Predicted to be involved in NAD metabolic process; lactate metabolic process; and pyruvate metabolic process. Predicted to act upstream of or within lactate biosynthetic process from pyruvate. Located in mitochondrion and myelin sheath. Is active in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human LDHB (lactate dehydrogenase B). PHENOTYPE: Electrophoretic variants of LDHB are determined by: the a allele with fast anodal mobility in all inbred strains tested; and the b allele with slower mobility in Peru-Coppock stock. Three additional variants are known in wild M. spretus from southern France and Spain. Alleles are codominant. [provided by MGI curators] |