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Protein Coding Gene : Dnai7 dynein axonemal intermediate chain 7
Primary Identifier  MGI:2444480 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  320662
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables beta-tubulin binding activity and microtubule binding activity. Predicted to act upstream of or within microtubule sliding. Located in cilium and cytoplasmic microtubule. Part of axonemal dynein complex. Orthologous to human DNAI7 (dynein axonemal intermediate chain 7).
PHENOTYPE: Mice with disruptions of this gene display a higher incidence of lung tumors. [provided by MGI curators]
  • synonyms:
  • cancer susceptibility candidate 1,
  • Las1,
  • Dnai7,
  • A230084G12Rik,
  • RIKEN cDNA A230084G12 gene,
  • dynein axonemal intermediate chain 7,
  • MGI:7414007,
  • lung adenoma susceptibility 1,
  • Casc1
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