Primary Identifier | MGI:1922250 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 232533 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in regulation of cellular component organization. Located in actin cytoskeleton and cytoplasm. Orthologous to human STK38L (serine/threonine kinase 38 like). PHENOTYPE: Homozygous gene-trapped mice exhibit premature dendritic branching of CA3 pyramidal neurons. Mice homozygous for a knock-out allele exhibit mislocalization of opsin, increased apoptosis and proliferation of interneurons in the inner nuclear layer and disrupted localization of amacrine cells. [provided by MGI curators] |