Primary Identifier | MGI:1336212 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 17086 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within defense response to virus and detection of virus. Located in cell surface. Orthologous to human NCR1 (natural cytotoxicity triggering receptor 1). PHENOTYPE: Mutations in this gene lead to alterations in susceptibility to viral infection induced morbidity/mortality, NK cell number, NK cell cytolysis, and T cell responses. [provided by MGI curators] |