| Primary Identifier | MGI:108278 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22192 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable NEDD8 transferase activity and ubiquitin-protein transferase activity. Involved in regulation of postsynapse assembly. Is active in glutamatergic synapse; postsynapse; and presynapse. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human UBE2M (ubiquitin conjugating enzyme E2 M). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, abnormal embryonic epiblast morphology, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
