| Primary Identifier | MGI:2154441 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 68077 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable 5S rRNA binding activity; identical protein binding activity; and p53 binding activity. Involved in negative regulation of signal transduction by p53 class mediator; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein localization to nucleolus. Located in nucleolus. Is expressed in nucleus pulposus. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor). PHENOTYPE: Homozygous knockout is pre-implantation embryonic lethal. Heterozygous knockout reduces incidence of chemically induced skin papilloma. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
