| Primary Identifier | MGI:1919684 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 72434 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable laminin binding activity. Predicted to be involved in negative regulation of smooth muscle cell apoptotic process. Predicted to act upstream of or within cell motility and cell-matrix adhesion. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including epithelium; foregut; sensory organ; skin; and thymus. Orthologous to human LYPD3 (LY6/PLAUR domain containing 3). PHENOTYPE: Homozygous null mice show no overt epidermal phenotype and have normal squamous epithelia morphology but are lighter and leaner than controls. Males display delayed wound healing whereas females show reduced food intake and a lower incidence of invasive lesions in a BBN-induced bladder cancer model. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
