| Primary Identifier | MGI:2142347 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 243905 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables transcription cis-regulatory region binding activity and transcription corepressor binding activity. Involved in embryonic placenta morphogenesis and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in central nervous system; retina; and skeletal musculature. PHENOTYPE: Homozygous null mutants are embryonic lethal with growth arrest around E8.5-9.0. Mutant embryo shows shortened anterior-posterior axial extension with defects in somites and midline structures including open gut tube, cardia bifida, and failure to closeneural tube. [provided by MGI curators] |